Single-molecule studies of the eukaryotic translation initiation factor 4A: helicase activity, conformational dynamics and function regulation
Thesis (Ph.D.)--Boston University === The PI3K/Akt/mTOR pathway regulates several cellular functions, including cellular proliferation, growth, and survival. The PI3K/Akt/mTOR pathway converges on the eukaryotic translation initiation factor 4F (eIF4F), making it an attractive molecular target for a...
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Language: | en_US |
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Boston University
2015
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Online Access: | https://hdl.handle.net/2144/11060 |