Single-molecule studies of the eukaryotic translation initiation factor 4A: helicase activity, conformational dynamics and function regulation

Thesis (Ph.D.)--Boston University === The PI3K/Akt/mTOR pathway regulates several cellular functions, including cellular proliferation, growth, and survival. The PI3K/Akt/mTOR pathway converges on the eukaryotic translation initiation factor 4F (eIF4F), making it an attractive molecular target for a...

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Bibliographic Details
Main Author: Sun, Yingjie
Language:en_US
Published: Boston University 2015
Online Access:https://hdl.handle.net/2144/11060