Screening methods for the development of binary spray-dried amorphous solid dispersions in early stage of drug and process development

Amorphous solid dispersion (ASD) of a poorly soluble active pharmaceutical ingredient (API) in a polymeric matrix is a promising approach to increase the solubility, dissolution rate and hence bioavailability of the API. From an industrial point of view, spray-drying represents the main solvent evap...

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Bibliographic Details
Main Author: Ousset, Aymeric
Published: University of Sunderland 2018
Subjects:
Online Access:https://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.766966