The biological role of the TNF super family ligand TL1A and its receptor DR3

Members of the Tumor Necrosis Factor superfamily of cytokines are an important source of costimulatory signalling required for the proper activation of T cells. One such receptor-ligand pair is Death receptor 3 (DR3) and its ligand TNF-like ligand 1A (TL1A). Genetic variants in TL1A are associated w...

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Bibliographic Details
Main Author: Ferdinand, John Robert
Other Authors: Al-Shamkhani, Aymen ; Taraban, Vadim
Published: University of Southampton 2016
Subjects:
Online Access:https://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.766743