eIF2B bodies and their role in the control of protein synthesis
The eukaryotic initiation factor 2B (eIF2B) serves as a vital control point within translation initiation. eIF2B initiates translation by exchanging GDP for GTP on eIF2. However, this mechanism may be attenuated in response to cellular stress by the phosphorylation of eIF2, which paradoxically enhan...
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Sheffield Hallam University
2018
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| Online Access: | https://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.766635 |