Development of tolerogenic plasmid vectors for gene therapy of Duchenne muscular dystrophy (DMD)

This project focused on the development of an effective gene replacement therapy for the Duchenne muscular dystrophy (DMD) in its mouse models [(X-linked muscular dystrophy, mdx) and mdx-βgeo mice]. Earlier studies on the DMD replacement therapy (usually using mini-dystrophin) were largely not succe...

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Bibliographic Details
Main Author: Sharma, Dishant
Other Authors: Gorecki, Dariusz Cezary ; An, Qian ; Sharpe, Colin Richard
Published: University of Portsmouth 2017
Subjects:
610
Online Access:https://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.765653