Does a senescene-like phenotype in neurons contribute to brain ageing and neurodegeneration?

Senescent cells accumulate in the body with age, and drive organismal ageing and tissue dysfunction. Senescence is not a simple growth arrest, but is accompanied by a host of phenotypic changes, including the generation of pro-inflammatory molecules, and is maintained by a network of auto- and parac...

Full description

Bibliographic Details
Main Author: Fielder, Edward Peter
Published: University of Newcastle upon Tyne 2018
Online Access:https://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.765373