Understanding the influence of adsorption-mediated processes on antibody aggregation in bioprocessing

Affinity chromatography is an indispensable method of protein purification used during the manufacture of many therapeutic antibodies. The protein A ligand is a popular choice for selective purification of immunoglobulin G (IgG) molecules. Aggregated product is often found in protein A elution pools...

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Bibliographic Details
Main Author: Mazzer, A.
Other Authors: Bracewell, D. G. ; Dalby, P. A. ; O'Hara, J.
Published: University College London (University of London) 2016
Subjects:
Online Access:https://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.763092