Investigation of the role of mTORC1 and MAPK/ERK pathways in cellular responses to amino acid deprivation

Sustaining proliferative signalling is one of the hallmarks of cancer. Cancer cells universally have high demands for nutrients to support their rapid proliferation. Studies presented in this thesis are focused on mTORC1 and MAPK/ERK signalling pathways, both of which promote cell growth and prolife...

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Bibliographic Details
Main Author: Wang, Xiaomeng
Other Authors: Vlatkovic, Nikolina ; Boyd, Mark
Published: University of Liverpool 2018
Online Access:https://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.762728