Neurodegenerative disease mechanisms induced by tau fragmentation in a novel model of human tauopathy

The tauopathies comprise a broad group of neurodegenerative diseases that are characterised by pathological alterations of tau in the brain that lead to synaptic dysfunction, changes in neuronal bioenergetics and loss of neuronal connectivity. There is growing evidence that tau fragmentation may be...

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Bibliographic Details
Main Author: Iankova, Natalia
Other Authors: Hanger, Diane Pamela ; Noble, Wendy Jane
Published: King's College London (University of London) 2018
Online Access:https://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.762392