Mechanisms of hyperexcitability and efficacy of antiepileptic drugs in hippocampal-entorhinal networks in the Reduced Intensity Status Epilepticus (RISE) model of chronic epilepsy

A third of epilepsy patients are resistant to anti-epileptic drug (AED) treatment leading to reduced quality of life, increased treatment costs and complexities surrounding polytherapy. The overall aim of this project was to explore dynamic network changes in the excitability and efficacy of AEDs in...

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Bibliographic Details
Main Author: Shah, Darshna
Published: Aston University 2017
Subjects:
Online Access:https://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.760134