Radiation effects on mesenchymal stem cells in a model of fibrosarcoma

Background: Radiotherapy is a mainstay of sarcoma treatment, but can cause fibrosis, characterized by production of extra-cellular matrix proteins such as collagen by cancer-associated fibroblasts (CAFs) in the cancer stroma and surrounding normal tissues, which makes tumours more aggressive and res...

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Bibliographic Details
Main Author: Aabed, Tariq Ahmad
Other Authors: Kanthou, Chryso ; Tozer, Gill
Published: University of Sheffield 2018
Subjects:
610
Online Access:https://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.759865