Investigating functional and biochemical consequences of p110 delta overactivity in innate immunity
Activated PI3Kδ syndrome (APDS) is a recently described primary immune deficiency characterised by gain-of-function (GoF) mutations in the PIK3CD gene which encodes the leukocyte-restricted p110δ catalytic subunit of phosphoinositide 3-kinase enzyme (PI3K) known to be important in cell survival, gro...
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University College London (University of London)
2018
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| Online Access: | https://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.756182 |