Drug induced degradation of driver proteins : a novel approach to target MLL-fusions
Acute leukaemias in infants are associated with inferior outcomes. The majority of infant acute leukaemia is characterized by balanced chromosomal translocations involving the mixed lineage leukaemia (MLL) gene. Previous work in the department established that the novel formed MLL fusions are the pr...
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University College London (University of London)
2018
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Online Access: | https://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.756174 |