Drug induced degradation of driver proteins : a novel approach to target MLL-fusions

Acute leukaemias in infants are associated with inferior outcomes. The majority of infant acute leukaemia is characterized by balanced chromosomal translocations involving the mixed lineage leukaemia (MLL) gene. Previous work in the department established that the novel formed MLL fusions are the pr...

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Bibliographic Details
Main Author: Cantilena, Sandra
Other Authors: De Boer, J. ; Williams, O.
Published: University College London (University of London) 2018
Online Access:https://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.756174