Computational studies of Glucocerebrosidase in complex with its facilitator protein Saposin-C
Gaucher’s Disease (GD) is a rare recessive disorder produced by the dysfunction of the lysosomal enzyme Glucocerebrosidase (GCase). GCase catalyses the cleavage of the glycolipid Glucosylceramide. The lack of functional GCase leads to the accumulation of its lipid substrate in lysosomes causing GD....
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University College London (University of London)
2018
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| Online Access: | https://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.756160 |