The role of NRF2 in acute myeloid leukaemia (AML)

Acute Myeloid Leukaemia refers to the excess proliferation of myeloid progenitor cells. Whilst the 5-year survival rate is 40% in younger patients, this falls to 5% in patients over 65 and resistance to front-line chemotherapy agents remain a problem. We previously identified NRF2, a regulator of an...

Full description

Bibliographic Details
Main Author: Shah, Niraj Mayank
Other Authors: MacEwan, David
Published: University of Liverpool 2018
Subjects:
Online Access:https://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.755734