A study of the molecular pharmacological properties of C5a and C5a des Arg : defining their biased agonist profile and contrasting biological function

The complement system provides an essential role in the orchestration of an effective immune response against microbial infection. Activation leads to the generation of C5a which activates receptors expressed on immune cells promoting microbial clearance. Dysregulation of the complement system that...

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Bibliographic Details
Main Author: Ramsey, S. J.
Other Authors: MacEwan, David ; Nicholas, Pullen
Published: University of Liverpool 2017
Subjects:
Online Access:https://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.755464