The involvement of SRSF1 in pre-mRNA splicing

The key splicing signals in pre-mRNA, the branch-point, 5’ splice site and 3’ splice site, are exceptionally poorly conserved in mammals. To compensate for this, key regulatory sequences are required to direct the reciprocal factors, U2AF, U1 snRNP and U2 snRNP respectively, to the correct sites. Th...

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Bibliographic Details
Main Author: Jobbins, Andrew Michael
Other Authors: Eperon, Ian ; Dominguez, Cyril
Published: University of Leicester 2018
Subjects:
570
Online Access:https://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.755367