Synthesis and functionalisation of highly substituted oxetanes : molecular scaffolds for drug discovery

This thesis details new approaches to the synthesis and functionalisation of highly substituted, diversely functionalised oxetanes (Scheme 1). These types of 2-substituted oxetanes constitute desirable 3-dimensional motifs for medicinal chemistry, which exhibit desirable physicochemical properties a...

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Bibliographic Details
Main Author: Davis, Owen Alexander
Other Authors: Bull, James
Published: Imperial College London 2016
Subjects:
540
Online Access:https://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.754662