Characterisation of the interleukin-4 signalling cascade involved in the induction of cyclooxygenase-2 and the polarisation of macrophages into an anti-inflammatory phenotype

The inflammatory response can be broken down into the pro-inflammatory phase, followed by the resolution phase. Both phases are regulated by the expression or release of immunomodulatory mediators such as cytokines e.g. TNFα and IL-10. The two phases are also associated with different macrophage pol...

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Bibliographic Details
Main Author: Manoj, Sivanjaa
Published: University of East London 2018
Online Access:https://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.753952