Characterisation of RNA polymerase II backtracking and its consequences in human cells

Transcription elongation by RNA polymerase II (RNAPII) is a highly complex process in which RNAPII moves by Brownian motion. Therefore, transcript elongation is a surprisingly interrupted process, including frequent pausing, backtracking and arrest (collectively referred to as transcription stress)....

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Bibliographic Details
Main Author: Zatreanu, Diana Alexandra
Published: University College London (University of London) 2018
Subjects:
570
Online Access:https://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.747795