Manipulating kinetochore function with synthetic physical interactions

The kinetochore is a large protein complex that assembles on centromeres. It enables accurate chromosome segregation by attaching chromosomes to the mitotic spindle via microtubules and by recruiting regulators that control mitosis. Many of these regulators modify kinetochore components by post-tran...

Full description

Bibliographic Details
Main Author: Olafsson, Gudjon
Published: University College London (University of London) 2018
Subjects:
570
Online Access:https://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.747219