A role for the Parkinson's disease kinase LRRK2 in endo-lysosomal and cytoskeletal function

Parkinson's disease (PD) is a progressive neurodegenerative disorder affecting millions of people globally. Like other age-related conditions, inheritance of genetic variations contributes to PD pathogenesis. Mutations in leucine-rich repeat kinase 2 (LRRK2) are linked with familial forms of la...

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Bibliographic Details
Main Author: Pellegrini, Laura
Published: University College London (University of London) 2017
Subjects:
Online Access:https://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.747128