Characterisation of dysfunctional Wnt/β-catenin signalling in the Down syndrome brain

Down syndrome (DS) is the most common human aneuploidy. It results from the presence of three copies, or trisomy, of human chromosome 21 (Hsa21). DS is associated with a plethora of characteristic clinical features, most notably learning disability, altered body morphology, congenital heart disease...

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Bibliographic Details
Main Author: Granno, S.
Published: University College London (University of London) 2017
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Online Access:https://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.747110