Towards defining the cellular and molecular function of the broad-spectrum antiviral IFITM proteins
The InterFeron Inducible TransMembrane proteins (IFITMs) are broad-spectrum antiviral factors. In vitro, these proteins inhibit cellular entry of many enveloped viruses. In vivo, mice lacking expression of all Ifitm genes, or Ifitm3 alone, have been shown to have increased pathogenesis from influenz...
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University College London (University of London)
2016
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| Online Access: | https://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.746362 |