The biological evaluation of inhibitors of the Keap1-Nrf2 protein-protein interaction
The Keap1-Nrf2 pathway has been identified as a key regulator of the cytoprotective response of cells when exposed to oxidative stress. The induction of detoxification gene products by increasing the activity of the transcription factor nuclear factor erythroid 2-related factor 2 (Nrf2) can be used...
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University College London (University of London)
2015
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| Online Access: | https://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.746044 |