Specific targeting of FcγRIIIa using artificial scaffold protein variants

Fcγ Receptors (FcγRs) are cell-surface receptors for IgG that are expressed on immune cells including macrophages, monocytes and natural killer (NK) cells. Upon binding to IgG-containing immune complexes, FcγRs trigger cell-mediated effector functions that lead to the clearance of pathogenic materia...

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Bibliographic Details
Main Author: Waterhouse, Mark Peter
Other Authors: Robinson, James I. ; Baxter, Euan W. ; Tomlinson, Darren C. ; Morgan, Ann W.
Published: University of Leeds 2018
Subjects:
610
Online Access:https://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.745561