The unfolded protein response : a potential link between heterozygous mutations in GBA1 and Lewy body dementia?

Lewy body dementia (LBD) is characterised by the deposition of a-synuclein containing Lewy bodies throughout cortical brain regions. Pathology is confounded by the co-occurrence of pathological Ab and tau deposition. LBD comprises dementia with Lewy bodies (DLB) and Parkinson’s disease dementia (PDD...

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Bibliographic Details
Main Author: Clarke, Emily Jayne
Other Authors: Broadstock, Martin ; Francis, Paul Thomas
Published: King's College London (University of London) 2018
Online Access:https://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.745388