Cascade cyclisation reactions and their application toward the synthesis of lactonamycin

The lactonamycins represent a class of natural products which possess significant biological activity with high potencies in cancer cell lines and against multi-drug resistant strains of bacterial infections. Here, a cascade cyclisation, developed in the Parsons group, has been used in the synthesis...

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Bibliographic Details
Main Author: Jones, Daniel Ross
Other Authors: Parsons, Philip
Published: Imperial College London 2018
Subjects:
540
Online Access:https://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.745320