Development of a non-mammalian, pre-clinical screening tool for the predictive analysis of drug toxicity

The failure to predict drug-induced toxicity reactions is still a major problem contributing to a high attrition rate and tremendous cost in drug development. Xenopus laevis embryos are amenable for the early stage medium to high throughput small molecule screens. We hypothesise Xenopus embryos can...

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Bibliographic Details
Main Author: Saide, Katy
Published: University of East Anglia 2018
Subjects:
570
Online Access:https://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.743359