ERAP1 inhibitor development

ERAP1 has been associated with a set of immune-mediated diseases, including ankylosing spondylitis. Currently, there is no selective and potent ERAP1 inhibitor available that would allow in-depth research of its functions and roles in diseases. Therefore, the aim of this work is to apply fragment-ba...

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Bibliographic Details
Main Author: Guzanov, Pavel
Other Authors: Brennan, Paul ; Oppermann, Udo
Published: University of Oxford 2017
Online Access:https://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.740954