Computational studies of structural motifs and cotranslational folding mechanisms in membrane and soluble proteins

Membrane proteins are an important class of drug targets, making up at least 25% of proteins in the human genome. In this thesis I investigated two aspects of alpha-helical membrane protein structures. Firstly, I investigated kinks in alpha-helices, many of which are thought to have functional roles...

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Bibliographic Details
Main Author: Law, Eleanor C.
Other Authors: Deane, Charlotte M. ; Kelm, Sebastian ; Shi, Jiye
Published: University of Oxford 2017
Online Access:https://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.740887