Development of novel predictive 2D and 3D in vitro models for anti-leishmanial drug testing

The failure rates of drugs once they reach clinical trials are high, with estimates up to nearly 90%. One reason is the lack of biologically relevant models in which potential drug candidates are screened, evaluated and selected during discovery and development phases. Leishmaniasis is a disease tha...

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Bibliographic Details
Main Author: O'Keeffe, A.
Other Authors: Croft, S. L. ; Murdan, S.
Published: London School of Hygiene and Tropical Medicine (University of London) 2018
Online Access:https://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.740139