Exploring the impact of anti-oestrogen resistance on the capacity of breast cancer cells to modulate bone cell function and their sensitivity to bisphosphonates
Acquired resistance to endocrine therapy is a major limiting factor for their clinical effectiveness, resulting in disease relapse and an associated poor prognosis. Acquired resistance is also associated with the development of an invasive and migratory phenotype in vitro that may promote metastatic...
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Cardiff University
2017
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Online Access: | https://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.738356 |