Synthesis of substituted tetrahydroquinolines using chiral organolithium chemistry
The tetrahydroquinoline (THQ) moiety is found in many natural products and compounds which have biological activity. This thesis describes the development of methodologies to carry out lithiation–substitution reactions of N-Boc-2-aryltetrahydroquinolines. Most of the THQ compounds fully deprotonated...
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University of Sheffield
2017
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| Online Access: | https://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.736534 |