Stereochemical aspects in the aminoalkylation reactions of ketones
A simple "one-pot" method has been developed for the amino-methylation of ketones possessing an α-hydrogen under aprotic conditions. The procedure utilises chlorotrimethylsilane in the sequential formation of the intermediate trimethylsilyl enol ether and methylene iminium species. The met...
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Loughborough University
1991
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Online Access: | http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.734118 |