Stereochemical aspects in the aminoalkylation reactions of ketones

A simple "one-pot" method has been developed for the amino-methylation of ketones possessing an α-hydrogen under aprotic conditions. The procedure utilises chlorotrimethylsilane in the sequential formation of the intermediate trimethylsilyl enol ether and methylene iminium species. The met...

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Bibliographic Details
Main Author: Fairhurst, Robin A.
Published: Loughborough University 1991
Online Access:http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.734118