Domain motions and complex formation in catalysis by NADPH-cytochrome P450 reductase

NADPH-cytochrome P450 reductase (CPR) is a multi-domain diflavin redox enzyme which is a key component of the P450 mono-oxygenase drug-metabolising system. This study was aimed to achieve an understanding of domain motions of human CPR which are believed to be intrinsic to its function and steps in...

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Bibliographic Details
Main Author: Freeman, Samuel Lewis
Other Authors: Roberts, Gordon C. K. ; Raven, Emma L. ; Martel, Anne ; Moody, Peter
Published: University of Leicester 2018
Subjects:
540
Online Access:https://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.733744