Structural and functional characterization of chaperones in Fe-S cluster biogenesis and regulation

Dysfunctions in Fe-S protein biogenesis and mitochondrial iron accumulation in heart and neurones are part of the phenotype of a genetic neurodegenerative disease called Friedreich's ataxia. This pathology is caused by the deficiency of a mitochondrial protein, frataxin, highly conserved throug...

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Bibliographic Details
Main Author: Puglisi, Rita
Other Authors: Pastore, Annalisa
Published: King's College London (University of London) 2017
Online Access:http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.733341