MET-EGFR dimerisation in lung adenocarcinoma is dependent on EGFR mutations and altered by MET kinase inhibition

Prognosis in advanced stage lung cancer is extremely poor with few effective therapies. EGFR tyrosine kinase inhibitors (TKIs) have high response rates in patients with activating EGFR mutations and are now an established part of therapy in selected patients. Such advances herald a previously unprec...

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Bibliographic Details
Main Author: Lee, Richard William
Other Authors: Ng, Tony Tsz-cheong ; Santis, George
Published: King's College London (University of London) 2017
Online Access:http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.733339