Epigenetic biomarkers for clinical outcomes and mechanisms driving emergence of drug resistance in ovarian cancer

Epithelial ovarian cancer (EOC) has a poor prognosis, with a 5 year survival rate of ~40%. A major therapeutic barrier is disease chemoresistant to the standard therapeutic regimen of taxol and platinum. Efficacious therapies in chemoresistant disease, a fuller understanding of the molecular mechani...

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Bibliographic Details
Main Author: Passey, Alun
Other Authors: Brown, Robert ; Wilhelm-Benartzi, Charlotte ; Ghaem-Maghami, Sadaf
Published: Imperial College London 2017
Subjects:
610
Online Access:https://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.733208