The development of a cellular model and mass spectrometry workflow for characterising protein tau in Alzheimer's disease
Background: Neurofibrillary tangles (NFTs) is one of the two ‘hallmarks’ of Alzheimer’s disease (AD). The main constitute of these tangles are known as the paired helical filaments (PHFs), which are essentially abnormal aggregate of microtubule associated protein Tau. It has been known for many year...
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Imperial College London
2016
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| Online Access: | https://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.733121 |