The epigenetic response to platinum-induced DNA damage and repair

The epigenetic response to platinum-induced DNA damage and repair

Platinum resistance causes treatment failure in a variety of cancers including ovarian cancer. Epigenetic changes can contribute to platinum resistance, as the epigenome is highly divergent between platinum-resistant and -sensitive cells, and DNA demethylating agents partially resensitise resistant...

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Bibliographic Details
Main Author:	Wilson, Angela
Other Authors:	Brown, Robert ; Flanagan, James
Published:	Imperial College London 2015
Subjects:	610
Online Access:	https://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.733062

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