The epigenetic response to platinum-induced DNA damage and repair
Platinum resistance causes treatment failure in a variety of cancers including ovarian cancer. Epigenetic changes can contribute to platinum resistance, as the epigenome is highly divergent between platinum-resistant and -sensitive cells, and DNA demethylating agents partially resensitise resistant...
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Imperial College London
2015
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| Online Access: | https://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.733062 |