A transthyretin-related gene and a neuroligin-like gene prevent 6-hydroxydopamine-induced dopaminergic neurodegeneration in C. elegans

The loss of dopaminergic neurons is a hallmark of Parkinson’s disease, the aetiology of which is thought to encompass increased levels of oxidative stress and protein misfolding. We used <i>C. elegans</i> to screen for genes that protect dopaminergic neurons from oxidative stress inflict...

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Bibliographic Details
Main Author: Offenburger, Sarah-Lena
Other Authors: Gartner, Anton
Published: University of Dundee 2016
Online Access:https://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.732375