Understanding the catalytic cycle of membrane pyrophosphatases through structural and functional studies

Membrane pyrophosphatases (M-PPases) couple pyrophosphate hydrolysis to the translocation of sodium ions/protons, using the resulting ion gradients to drive abiotic stress resistance and in the infectivity of protozoan parasites. I have solved two M-PPase structures in different catalytic states, co...

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Bibliographic Details
Main Author: Wilkinson, Craig
Other Authors: Goldman, Adrian ; Muench, Stephen
Published: University of Leeds 2017
Subjects:
570
Online Access:https://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.731512