Interactions between the Nrf2 antioxidant response and mammalian iron homeostasis

Iron is an essential micronutrient as it contributes to the oxygen-carrying capacity of blood and is a cofactor for many enzymes. However, excess iron is toxic as it promotes the formation of reactive oxygen species (ROS), which react with and alter the functions of biomolecules. Moreover, there is...

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Bibliographic Details
Main Author: Lim, Pei Jin
Other Authors: Drakesmith, Alexander Hal
Published: University of Oxford 2017
Online Access:http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.729562