The role of the HSV-1 ICP22 protein in regulation of expression of host cell genes

The eukaryotic RNA Polymerase II (Pol II) is responsible for the synthesis of all mRNA and many small regulatory RNAs. The Herpes Simplex Virus 1 (HSV-1) relies exclusively on the host Pol II to synthesise viral RNA during productive infection. A repeating structure on the carboxy terminal domain (C...

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Bibliographic Details
Main Author: Isa, Nur Firdaus
Other Authors: Murphy, Shona
Published: University of Oxford 2017
Online Access:http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.729098