The role of dendritic cells in determining the breadth and epitope specificity of the initial CD8+ T cell response during acute HIV-1 infection
During acute HIV-1 infection (AHI), CD8+ T cell responses are initially induced to only 1-3 viral epitopes in many patients, and Nef-derived epitopes are very commonly targeted. The earliest CD8+ T cell responses decrease in magnitude as viraemia begins to decline, and are followed by delayed expans...
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University of Oxford
2016
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| Online Access: | http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.728959 |