Investigation of the pseudokinase TRIB2 : a double-edged sword in AML

TRIB2 belongs to the TRIBBLES family of serine/threonine pseudokinases (TRIB1, TRIB2 and TRIB3). TRIBBLES regulate proliferation, survival, differentiation, metabolism and stress responses, and their expression is frequently deregulated in cancer, including Acute myeloid leukaemia (AML). AML is a he...

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Bibliographic Details
Main Author: Salomè, Mara
Published: University of Glasgow 2017
Subjects:
Online Access:https://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.726730