Mechanisms involved in the development of androgen independent prostate : androgen receptor activation leads to a dissociation of E2F1:PHB in prostate cancer

Prostate cancer (PC) is the most common cancer found in men in the Western world. Predominantly, the pathogenesis of PC is driven by aberrant androgen receptor (AR) signalling, resulting in heightened cell proliferation and cell survival. Current treatment options target the AR signalling cascade by...

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Bibliographic Details
Main Author: Koushyar, Sarah
Published: Cardiff University 2017
Subjects:
Online Access:https://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.725706